A 2012 paper studied the effect of supplementation with BCAA on proteolysis markers.
In this study, the effects of taking BCAA and taking a placebo on the proteolysis markers (MAFbx mRNA and MuRF-1) were compared.
It is found that supplementation of BCAA does have an effect on these two markers, but the research in this direction is not accurate enough.
A 2011 study by Nagoya University. For mice that have lost their exercise capacity and are in a state of muscle atrophy, they are given BCAA supplement. It is found that although muscle atrophy cannot be controlled, it can inhibit the loss of myofibril.
Another experiment is more interesting.
The team also found a piglet experiment from Huazhong Agricultural University in 2016.
Adding BCAA to the piglet feed of low-protein diet helps to promote the protein synthesis of the piglets. This effect is greater than the inhibition of protein decomposition.
In other words, BCAA can play a certain role only when it matches the diet.
Some of the above studies tell us:
(1) BCAA seems to be effective in inhibiting protein breakdown caused by exercise, but there are too many interference factors and it is not clear.
(2) In the case of lack of protein intake, supplementation of BCAA with diet seems to be able to inhibit decomposition more clearly.
(3) Of course, if it is a paralyzed state of muscle atrophy, it may also have an anti-decomposition effect, but the muscle atrophy cannot be reversed.