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Is Excessive Intake Of Lycopene Harmful?

Feb 22, 2021

Simply put, if it is taken through natural foods, lycopene is not easy to overdose. However, you may need to pay attention if you take additional supplements.

Lycopene is the most important carotenoid and has a variety of physiological activities. The current research shows that it has a strong antioxidant effect, which is of positive significance to human health.

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Therefore, people have conducted a lot of research on its absorption and distribution in the body. At present, the lycopene in heat-processed tomato juice is easier to absorb than unprocessed tomato juice. The lycopene in food is divided into cis and trans chemical structures, and the absorption rate is also different. Therefore, the higher the lycopene content of food intake, the more the body absorbs, but it is not a linear relationship.

Lycopene is widely present in nature, such as tomatoes, watermelons, grapefruits, etc. The content can vary with the variety and maturity.

Lycopene is a fat-soluble compound. It must have a fat environment for its absorption and transport in the body to improve its bioavailability. Generally speaking, after lycopene enters the body, it penetrates into the chylomicrons through the small intestinal mucosal cells, and then is released into the lymph and blood, where it is transported with low-density lipoprotein as a carrier. Lycopene is mainly stored in the liver in the body. In addition, the concentration is also higher in plasma, adrenal gland, corpus luteum, testis, and prostate.

Although there are not too many studies on the adverse effects of high-concentration lycopene intake, it is better to consume non-natural substances such as lycopene health products in moderate amounts. Even if it is harmless to the human body, eating more can hurt the wallet.