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What Are The Preparation Processes Of Ferulic Acid?

Apr 14, 2021

At present, there are many preparation techniques for ferulic acid. In summary, there are mainly two types of methods, namely, artificial chemical synthesis and extraction from plants. (1) The artificial chemical synthesis method is one of the commonly used methods for preparing ferulic acid. The simple process uses vanillin aldehyde and malonic acid as raw materials, anhydrous pyridine as solvent, piperidine as catalyst, and artificially synthesized ferulic acid is obtained through condensation reaction. For example, ferulic acid piperazine salt has been synthesized in China. (2) Preparation and extraction of ferulic acid from plants. This type of method can obtain ferulic acid from plants in three ways. First, it is obtained from the combination of ferulic acid and some small molecules; second, it is obtained from the cell walls of some plants, in addition to Angelica and Ligusticum chuanxiong, there are also Weilingxian, Leonurus, Jujube Seed, Sanyu, Ligusticum chinense Ferulic acid can also be extracted from Chinese herbal medicines such as konjac, propolis and Duhuo. Third, it can be obtained through tissue culture of certain cells. For example, many of the sodium ferulate (SF) currently used in China are derived from traditional Chinese medicine for promoting blood circulation and removing blood stasis. Extracted from Angelica sinensis and Ligusticum chuanxiong.