How To Produce Arachidonic Acid?

Jun 17, 2022 Leave a message

The natural sources of arachidonic acid are mainly animal adrenal glands, liver, fish oil, and egg yolk. However, the ARA content in animal tissues is very low, about 2%, and is easily affected by environmental factors such as climate and origin. ARA is also found in some fungi and microalgae, and the production of ARA by microbial fermentation is the predominant method on the market.

Arachidonic Acid powder

What Does ARA Do for Babies?

As a natural component of breast milk, ARA is essential for the infant's neurological and physiological development and has special significance for the infant's growth and development and for the perfect functioning of the brain and retina. It is considered an essential nutrient for early human development.

How To Get Arachidonic Acid Powder?

Mortierella is a high-producing strain of ARA, and marine microalgae are also good producers of polyunsaturated fatty acids. For the production of ARA, separation and extraction technology is one of the keys to ensure product quality.

There are five commonly used ARA isolation and extraction techniques:

1. Extraction: Since ARA exists in the oil in the form of non-polar triglycerides, ARA and other PUFAs can be separated out using a suitable non-polar solvent.

2. Supercritical CO extraction of Mortierella oil: This method utilizes the very unique physicochemical properties of supercritical fluids, such as good solubility close to liquid and transport characteristics close to gas, to extract the effective components of natural substances.CO is widely used as a supercritical fluid extractant due to its low critical parameters (7.37 MPa, 304.1 K), non-toxic and harmless, low price, and easy availability.

3. High performance liquid chromatography separation and purification of microbial oil: In order to obtain better separation effect, the fatty acids obtained from microbial oil were first methylated by urea encapsulation method, and then separated and purified by reversed-phase high performance liquid chromatography.

4. The enrichment of microbial oil by urea encapsulation method.

5. Extraction and purification method of silver ion complex.

HSF is the leading manufacturer of Arachidonic Acid Powder by microbial fermentation. Relying on advanced technology, HSF is equipped with modern production equipment, follows scientific production processes, produces strictly according to international production technical standards, and provides customers with high-performance and high-quality ARA powder with excellent service.


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