Natural Beta-Carotene Powder

Ingredients Sheet

Specification

Preparation Methods

Screening and optimization of natural strains

Construction of strain library: Collect more than 3,000 strains of natural microorganisms to establish a dedicated strain resource library.

High-throughput screening technology: Using microfluidic chip technology, an average of 500 strains are screened per day, and finally locked in Blakeslea trispora HSF-Bt07, whose β-carotene synthesis capacity is 3 times that of wild strains.

Adaptive evolution technology (ALE): Through long-term stress culture (such as high osmotic pressure and low temperature), the strain's stress resistance is enhanced, and there is no yield attenuation after 20 generations of continuous fermentation, and the stability reaches 99%.

Fully enclosed intelligent fermentation system: fermentation technology + intelligent equipment dual engine, the final solution to the problem of light-oxygen sensitivity

Light-proof and oxygen-controlled design: double-layer stainless steel fermentation tanks are used, with anti-ultraviolet coating on the outside and nitrogen covering system integrated inside, and the dissolved oxygen content is controlled at DO≤3% (industry average 8%) throughout the process.

Dynamic control technology:

Real-time monitoring: embedded sensors collect 12 parameters such as pH, temperature, and bacterial density every 10 seconds;

Intelligent feeding: based on machine learning algorithms, accurately predict the carbon-nitrogen ratio (C/N) requirements, automatically adjust the feeding rate, and increase the bacterial density to 65g DCW/L (traditional process 40g DCW/L).

Two-stage fermentation strategy:

High-density proliferation period: optimize the culture medium formula, and the biomass increases by 300% within 48 hours;

High-efficiency hormone production period: trigger metabolic bursts through gradient temperature increase, and the β-carotene production reaches 10g/L, which optimizes the fermentation cycle to the greatest extent.

Extraction technology: balance between green process and high purity

Low-temperature and high-efficiency extraction: selectively extract β-carotene under mild conditions of 35℃ and 0.6MPa to avoid high temperature damage to the isomer structure.

Multi-stage separation and purification:

Primary separation: recover the solvent by reduced pressure evaporation, with a recycling rate of 98%;

Zero chemical addition: no strong acid, strong base or heavy metal catalyst is used throughout the process, in line with EU EC 1333/2008 food additive safety standards.

Full-process quality control system: 18 potential impurities are detected by HPLC-MS, and the entire production process data is traced and queried.

Thousand-ton intelligent production line: a breakthrough in large-scale production

The leading large-scale production line in China: Starting from 2022, HSF has built a fermentation production line that can perfectly display the accumulation of HSF's R&D technology. This fermentation production line brings together more than ten years of wisdom of Mrs. HSF.

Modular design: The production line can flexibly adjust the production capacity (500-2000 tons/year), complete product switching within 72 hours, and meet the diverse needs of customers.

Green manufacturing: The fermentation waste liquid is filtered through membranes to recover bacterial protein (used as a feed additive), and carbon emissions are reduced by 60% compared with traditional processes.

Invention Patent

An 8-carotene-producing Rhodobacterium sphaeroides engineered strain and construction method thereof

 

Relying on the "science-technology-industrialization" research and development innovation system, HSF uses microfluidic chip technology to lock in Blakeslea trispora HSF-Bt07 among more than 3,000 natural microorganisms and strengthens the strain's stress resistance through long-term stress culture (such as high osmotic pressure and low temperature). It has achieved 20 consecutive fermentations without yield attenuation and a stability of 99%.

 

 

 

 

In order to solve the problem that traditional beta-carotene oil-soluble products are difficult to disperse and easy to degrade, HSF launched water-soluble β-carotene powder and nanoemulsion based on VegeLipi^® microencapsulation technology, and provides customized dosage forms (tablets, soft capsules, beverage additives) according to customer needs.

Flow Chart

HSF Beta-Carotene Series

Applications

Our natural beta carotene finds wide applications in different businesses, including pharmaceuticals, nutraceuticals, beauty care products, and nourishment. It serves as a key fixing in dietary supplements, skincare definitions, and nourishment fortification.

Food industry: β-carotene is widely used in coloring and nutritional fortification of foods such as margarine, capsules, fish paste products, vegetarian products, instant noodles, etc. Microencapsulated β-carotene can be converted into water-soluble pigments and can be used in almost all foods.

Feed industry: As an additive for animal feed, it improves the nutritional value and coloring effect of feed.

Pharmaceutical industry: As a colorant and nutritional supplement for medicines, it is used to make tablet sugar coatings, etc.

Cosmetic industry: Used to make cosmetics with antioxidant and anti-aging functions.

Storage and Package

Qualification

Certificates such as ISO9001, ISO22000, FAMI-QS, IP(NON-GMO), Kosher, Halal are in place.

Worldwide Exhibitions

Factory View (Click for video details)

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