Is inositol so magical?

Inositol was first discovered in animal muscles. It is a water-soluble vitamin, but it is not a real vitamin because the human body can synthesize myo-inositol from glucose. It is an essential nutrient for cell growth and survival, and is one of the substances that make up the phospholipid bilayer (cell membrane scaffold).

Inositol is a hexacarbonylcyclohexane of the cyclohexanol family, commonly known as myocardial sugar, and is a vitamin product. Myo-inositol is a growth factor, and almost all organisms contain myo-inositol in free or bound form. China is rich in rice, and the main raw material for the production of inositol is rice bran. Therefore, China has always been the main producer and exporter of inositol. As a by-product of degreasing rice bran, inositol is widely used in a variety of industries. With the deepening of research, people's demand for inositol is also increasing, and the market development potential is huge.

As the second messenger of the human body, myo-inositol is responsible for stimulating various hormones in the human body to perform their proper functions and can regulate the activity of different hormones. Many hormonal reactions in the human body require the participation of myo-inositol. Includes: thyroid-stimulating hormone (TSH), vasopressin, angiotensin, GABA, serotonin, insulin, luteinizing hormone (LH), and follicle-stimulating hormone (FSH).

Optimizing fertility

Inositol can relieve insulin resistance and help reduce LH secretion. Secondly, gonadotropin-releasing hormone (GnRH) from the hypothalamus triggers the pituitary gland to release LH and FSH signals, and its second messenger is myo-inositol. Although the pituitary gland is its primary target, ovarian follicles also contain GnRH receptors, so its signaling can have a direct regulatory effect on them.

Inositol promotes high-quality oocytes and follicle maturation even in women without polycystic ovary syndrome (PCOS). Furthermore, myo-inositol can assist sperm movement, acrosome reaction, and fusion of sperm and oocytes, increase sperm quantity and concentration, and rebalance LH, FSH, and inhibin B. Therefore, both men and women who want to prepare for pregnancy can supplement myo-inositol.

Regulates thyroid-stimulating hormone (TSH) levels

In addition to LH and FSH, myo-inositol also acts as a second messenger for TSH, which is also produced by the pituitary gland. Research shows that myo-inositol helps regulate thyroid-stimulating hormone (TSH) levels, which is important in monitoring hypothyroidism.

Improve metabolic syndrome

Metabolic syndrome is a group of symptoms of metabolic disorders of proteins, fats, carbohydrates and other substances, including insulin resistance (IR), hyperinsulinemia, abnormal blood sugar, dyslipidemia and hypertension. It is a risk factor for cardiovascular disease. Patients with metabolic syndrome can effectively improve their metabolic status by supplementing myo-inositol, which can help reduce triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), fasting blood sugar levels and blood pressure. For healthy people, supplementing myo-inositol can also exert a similar effect on regulating glucose and lipid metabolism, helping to improve IR and regulate carbohydrate metabolism.

Improve insulin resistance (IR)

Inositol is the precursor of inositol phosphate polysaccharide (IPG), which can be divided into MI-IPG and DCI-IPG according to the different inositol isomers contained. Both serve as second messengers and play important mediating roles in the insulin signaling pathway. Inositol exerts an insulin-like effect through the insulin signaling pathway mediated by IPG. When insulin binds to the insulin receptor on the cell membrane to form an insulin receptor substrate, IPG acts as a second messenger and activates phosphatidylinositol 3-kinase (PI3K),promote the translocation of glucose transporter (GLUT) 4 to the cell membrane, increase the uptake and utilization of glucose by peripheral tissues, thereby improving the IR status of peripheral tissues.

The insulin-like effect of myo-inositol can reduce insulin production and improve IR, thus exerting beneficial effects on endocrine and metabolism. Studies have proven that myo-inositol can reduce IR in PCOS patients, regulate menstrual cycles, and restore spontaneous ovulation in the ovaries.

Improve depression and anxiety

Inositol helps increase cell sensitivity to serotonin, enhances signaling of the calming neurotransmitter GABA, helps release calcium stores in the brain, stimulates the release of serotonin and GABA, and can promote feelings of calm and well-being. Due to its importance to brain function, myo-inositol can help treat many mental health issues such as depression, anxiety, and obsessive-compulsive disorder. For anxious patients with panic attacks, inositol is often given. In a double-blind experiment, 4g of myo-inositol three times a day was found to control panic in patients; in another double-blind experiment, researchers found that 18g of inositol per day could alleviate the symptoms of obsessive-compulsive disorder.

In addition, studies have found that myo-inositol can act as an antidepressant, which is helpful for people with anxiety, especially premenstrual dysphoric disorder (PMDD). Depression is a complex condition that can be triggered by many factors and can be affected by neurotransmitter levels and even gut health. Inositol can have a balancing effect on chemicals in the brain that interact with dopamine and serotonin, two neurotransmitters that are critical for balancing mood and have inhibitory effects on depression.

Food industry

Inositol can synthesize creatine phospholipids, membrane phospholipids, sphingolipids and other substances, participate in metabolic activities in the body, and is an indispensable substance for the growth of human cells. Inositol is often added as a nutritional fortifier in health drinks and children's foods. As early as 1987, the United States recommended adding a certain amount of myo-inositol to baby food. The content of free myo-inositol in the blood of normal people is 0.41~0.76 mg/dL. If the human body lacks myo-inositol, the fatty acids in the diet will be easily synthesized in the liver, and a large amount of triglycerides will accumulate, which is very detrimental to human health. At this time, the role of myo-inositol comes to the fore. Myo-inositol can interact with sarcoidine in the human body to quickly convert fat into calories and be consumed to prevent fat from being deposited in the body, especially in the cardiovascular system. Therefore, weight loss and lipid-lowering products added with myo-inositol are favored by many countries in Europe and America.

Pharmaceutical industry

Inositol is a low-molecular organic substance that is essential for normal physiological activities of humans and animals. It has vitamin B1 and biotin-like effects, which can treat multiple vitamin deficiencies; it can promote liver fat metabolism. Inositol also has the ability to lower blood cholesterol levels and is effective in disorders of fat and cholesterol catabolism. In addition, an appropriate amount of myo-inositol can also prevent hair loss; for women with polycystic ovary syndrome, appropriate intake of myo-inositol can improve insulin sensitivity and ovulation function caused by metabolic syndrome.

Feed industry

Inositol is an essential nutrient for aquatic animals and plays an important role in maintaining their normal physiological functions. Inositol is often added to the feeds of crustacean and fish animals as a nutritional fortifier to promote the growth and development of aquatic organisms. If fish or crustaceans do not take in enough myo-inositol, they will have symptoms such as poor appetite, slow growth, cracked dorsal fins, and bloated bellies. At the same time, it is difficult to convert feed into nutrients needed by aquatic organisms, resulting in a waste of resources. Through research, it was found that adding inositol to goldfish feed can significantly improve the swimming ability of goldfish.

By adding different contents of myo-inositol to the feed, after eight weeks of feeding, it was found that when the inositol content was 4000 mg/kg, the juvenile shrimp grew the fastest and had the highest protein utilization rate in the feed. When the myo-inositol content was 350 mg/kg, the growth rate of tilapia juveniles was significantly higher than that of other groups. The optimal content of myo-inositol added to the feed is 166~214 mg/kg, which not only ensures the nutrition of young grass carp, but also promotes the growth of their protein, and does not cause excessive intake of myo-inositol and cause a waste of resources. At the same time, the researchers also found that the triglyceride content in the blood of pomfret ovata that consumed feed supplemented with myo-inositol was significantly lower than that of the group that did not consume feed containing myo-inositol. It can be seen that adding an appropriate amount of myo-inositol to aquatic organism feed can not only promote the growth of aquatic organisms, but also improve protein utilization.

Cosmetics industry

As a raw material for the production of multivitamins, inositol is not only used in the pharmaceutical, food and feed industries, but also can be added to cosmetics as a cosmetic additive. It can promote cell growth, delay aging, inhibit the formation of melanin, and prevent freckles. Adding an appropriate amount of myo-inositol to shampoo can also promote hair regeneration and prevent hair loss. In recent years, major high-end cosmetics brands have begun to add inositol, and inositol is very popular in the international market.

HSF is a manufacturer specializing in the production of inositol. Inositol is extracted from high-quality corn after processing with HSF's advanced technology and equipment. It has high purity and good crystallinity. Mainly used in medicine, food, health products, cosmetics and other fields.

We can provide inositol powder in different concentrations or formulations to meet the needs of different users.

For more details, please contact us:

Email: sales@healthfulbio.com

Whatsapp: +86 18992720900