Normal individuals typically shed no more than 100 strands of hair per day. If the amount exceeds this limit, it may be defined as a hair loss disorder. Hair loss disorders are common and difficult to treat conditions, including non-scarring alopecia and scarring alopecia. They are primarily influenced by factors such as androgens, stress, environment, metabolism, age, and nutrition. The most prevalent types of hair loss disorders are androgenic alopecia, alopecia areata, and telogen effluvium. Hair loss patients often exhibit deficiencies in certain nutrients, vitamins, or trace elements.
Nutritional supplements refer to supplements that contain multiple nutrients derived from natural sources, such as animal and plant extracts, or artificial formulations or synthesis. Their main components include vitamins, trace nutrients, and others. In recent years, researchers have gradually begun to focus on the therapeutic effects of nutritional supplements on hair loss disorders, and many ingredients have shown promising results. Numerous products have gained widespread recognition in the market. Nutritional supplements can serve as effective complements to current drug treatments or be used alone to treat mild hair loss or meet daily maintenance needs.
Trace Nutrients
Vitamin D: Vitamin D has anti-inflammatory and immune-regulatory effects. Studies have found that patients with alopecia areata have significantly lower serum vitamin D concentrations, and the proportion of vitamin D deficiency is higher. However, there is no significant correlation between serum vitamin D concentration and the severity of hair loss. It is necessary to check the serum vitamin D concentration of patients with alopecia areata, and vitamin D deficiency should be supplemented with oral or topical medication. In addition to alopecia areata, vitamin D deficiency may also be related to other hair loss disorders such as androgenic alopecia, telogen effluvium, frontal fibrosing alopecia, and lichen planopilaris.
Vitamins: B vitamins contain multiple water-soluble vitamins, among which vitamin B2 (riboflavin), vitamin B7 (biotin), folic acid, and vitamin B12 (cobalamin) are most closely related to hair loss. The proportion of biotin deficiency is higher in hair loss patients, and it is beneficial to supplement biotin for these patients.
Iron and Zinc: Iron deficiency is common in female hair loss, especially in telogen effluvium. Serum ferritin concentration can better represent the body's iron stores. It is recommended for patients with ferritin levels below 60μg/L to take oral iron supplements. Zinc is a component or activator of various zinc-containing enzymes, participating in the metabolism of multiple substances in the body. Zinc deficiency can lead to widespread hair changes, including telogen effluvium and brittle hair.
HSF Biotech specializes in the production of food-grade vitamin B7 (biotin) with a purity level of over 90%. Their biotin serves as a key ingredient for nutritional supplements targeting hair nourishment. HSF Biotech's high-quality biotin is sourced from natural ingredients and undergoes a rigorous manufacturing process to ensure its purity and effectiveness. The food-grade designation guarantees that the biotin meets stringent safety and quality standards, making it suitable for consumption.
In the formulation of hair nutritional supplements, HSF Biotech's biotin acts as a foundational ingredient due to its well-established benefits for hair health. By supplementing with biotin, individuals may experience improved hair growth, reduced hair loss, and enhanced overall hair quality. HSF Biotech's commitment to providing premium biotin for hair supplements demonstrates their dedication to offering effective solutions for hair care. The high purity level of their biotin ensures that users can trust the quality and reliability of their products.
Immunomodulators and antioxidants
- Astaxanthin: Astaxanthin is a type of carotenoid mainly derived from Haematococcus pluvialis. As an antioxidant, its potency is 6,000 times that of vitamin C and 550 times that of vitamin E. The structure of astaxanthin contains multiple polyene chains, which can capture oxidative free radicals in cell membrane structures and reduce oxidative stress levels in mitochondria. Additionally, astaxanthin has anti-inflammatory effects by blocking the activation of NF-K B, reducing the expression of pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-a.
- Curcumin: Curcumin possesses various properties including anti-inflammatory, antimicrobial, antioxidant, and anti-tumor activities. The active component of curcumin, namely curcumin, is a 5a-reductase inhibitor that can inhibit the conversion of testosterone to dihydrotestosterone, suppress NF-kB, promote apoptosis, and reduce the expression of various inflammatory factors such as TNF-a and interleukins.
- Piperine: Piperine is derived from black pepper and exhibits significant dose-dependent immunomodulatory, anti-inflammatory, antioxidant, and anti-tumor activities. In animal models, piperine demonstrates 5a-reductase inhibitory effects and promotes hair growth. It can eliminate various oxidative free radicals, protect tissues from oxidative damage, and enhance the bioavailability of other nutritional supplements.
Hormone regulator
- Capsaicin and isoflavones: Capsaicin is a common food additive, and isoflavones are plant estrogens mainly found in legumes. Topical application of capsaicin and isoflavones can promote the generation of Insulin-like Growth Factor 1 (IGF-1) in the skin, which plays an important role in hair growth.
- Ashwagandha (Indian Ginseng): Ashwagandha is rich in a steroid-like ester called harpagoside, which interacts with certain corticosteroid receptors to regulate cortisol levels and reduce stress responses.
- Maca Root: Maca root is derived from Peru and is rich in essential amino acids, fatty acids, and other nutrients such as vitamin C, polyphenols, copper, iron, and calcium. It has various effects including anti-inflammatory and immunomodulatory properties.
In the treatment of hair loss diseases, there has been a rapid advancement in various therapeutic approaches including medication, physical therapy, immunomodulation, and the increasingly recognized use of nutritional supplementation. Nutritional supplements are now receiving more attention as they can be used alone or in combination with existing treatment regimens. HSF Biotech produces natural ingredients such as biotin, astaxanthin derived from Haematococcus pluvialis, turmeric fermented with lactobacillus, Ashwagandha, and Maca Root. These natural ingredients are used in the formulation of nutritional supplements for hair loss and hair care.
The combination of these natural ingredients in nutritional supplements provides a comprehensive approach to supporting hair health and addressing hair loss concerns.
