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Other effects of plant sterols

Oct 01, 2021

Stigmasterol

A large number of studies have found that plant sterols have a certain significance in reducing the incidence of male prostatic hypertrophy.

Classical studies such as Berges et al. (1995) conducted an intervention study on 200 patients with benign prostatic hypertrophy. The results found that after 6 months of supplementation with β-sitosterol, the experimental group was either from maximum urinary speed, residual urine output, or symptoms The score value and other aspects are better than the control group (P<0.01), and the effect can last for at least 18 months. Many other population studies have reached similar conclusions (Berges et a1., 2000).

Epidemiological studies have shown that dietary intake of plant sterols is negatively correlated with the incidence of cancers such as prostate cancer, ovarian cancer, and gastric cancer. The research results of McCann et al. (2003) showed that dietary intake of β-sitosterol (478-861 mg/d), campesterol (26-32 mg/d) and stigmasterol (> 23 mg/d) and the occurrence of ovarian cancer Negative correlation. De et al. (2000) conducted a study on Uruguayans and found that the intake of plant sterols was negatively correlated with the incidence of gastric cancer.

Some scholars have proposed that phytosterols may have antioxidant functions. For example, in the oxidized methyl linoleate solution, the antioxidant effects of various phytosterols from high to low are campesterol>β-sitosterol>stigmasterol (Normen et al., 2001).

The latest research also shows that stigmasterol has the effect of inhibiting the formation of pro-inflammatory substances and accelerating their degradation. (Gabay et al., 2010).